Applied Biochemistry II was offered again for the Winter Program of the Program of the Gifted and Talented. It was the fourth offering after 2022, 2021, and 2019. The course was held on 30 December 2023 and 6 January 2024 with 22 motivated students. With compared with previous classes, there were 20 students in 2022, 16 in 2021; it appeared the class size of this course was still increasing slowly. Owing to the great demand of STEM courses these days, I will continue to offer a bit more courses as far as I can.